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However, the FDA added a warning to testosterone product labeling after reviewing five observational studies and two meta-analyses of RCTs that examined the effects of testosterone therapy on MACE. Two of the trials and one meta-analysis pointed to an increased risk of cardiovascular events, 363, 364, 366 two revealed no cardiovascular risk, 233, 367 and one was neutral with respect to risk. Although the committee reviewing the evidence concluded that there was not enough data to definitively state that testosterone therapy posed a significant cardiovascular risk, the FDA nonetheless required testosterone product manufacturers to add information to the labeling about a possible increased risk of myocardial infarction and cerebrovascular accidents in patients using testosterone therapy, . Two of the retrospective studies included in the FDA review pointed to an increased risk of cardiovascular events in men on testosterone therapy.. prix commander anabolisants stéroïdes en ligne cycle. 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